Friday, June 7
viruses, vlps & nanoparticles
8:30 AM – 9:00 AM Registration (at the registration desk in Portus Congress Center)
Session Chairs: Ivana Petrović Koshmak (Sartorius BIA Separations) and Urh Černigoj (Sartorius BIA Separations, Slovenia)
9:00 AM – 9:35 AM Orthogonal chromatography analytics to allow for faster process development and better in-process control (Aleš Štrancar, Sartorius BIA Separations)
9:35 AM – 10:00 AM Gene therapy for retinal disorders – achievements and remaining challenges (Stylianos Michalakis, LMU Hospital) – Online
10:00 AM – 10:25 AM Key points of process development and characterization of AAV gene therapy products (Ella Chan, Skyline)
10:25 AM – 10:55 AM Coffee Break
Session Chairs: Manfred Reiter (Nuvonis, Austria) and Maja Leskovec (Sartorius BIA Separations, Slovenia)
10:55 AM – 11:20 AM Vesicles and vehicles; EVs on the road to clinics (Jens Gruber, Curexsys)
11:20 AM – 11:45 AM Separation and functional characterization of stem cell-derived exosomes from scalable manufacturing processes (Klaus Graumann, Phoenestra)
11:45 AM – 12:10 PM Mechanistic modeling for the purification of a replicant-competent enveloped virus on a monolithic ion-exchange chromatography (Adrian Schimek, ViraTherapeutics)
12:10 PM – 1:10 PM Lunch in the Congress Center (provided by the organizer)
Session Chairs: Beata Halassy (University of Zagreb, Croatia) and Sebastijan Peljhan (Sartorius BIA Separations, Slovenia)
1:10 PM – 1:45 PM The CCX cell line, a novel avian substrate for efficient virus production and seamless (CIM based) virus purification (Manfred Reiter, Nuvonis)
1:45 PM – 2:10 PM delNS: Harnessing interferon induction and antigen expression for enhanced immunotherapy against cancer (Thomas Muster, BlueSky Immunotherapies) – Online
2:10 PM – 2:35 PM Efficient purification of lymphocytic choriomeningitis virus using monolithic chromatography (Binod Prasad, Abalos Therapeutics)
2:35 PM – 3:00 PM Process development for an oncolytic rhabdovirus (Michaela Smolle, ViraTherapeutics)
3:00 PM – 3:30 PM Coffee Break
Session Chairs: Manuela Bartolini (University of Bologna, Italy) and Djuro Josić (University of Pula, Croatia)
3:30 PM – 3:45 PM YRC: High-throughput sequencing approaches for in-depth analysis of AAV-based gene therapies (Mojca Janc, National Institue of Biology)
3:45 PM – 4:00 PM YRC: Production and purification of Staphylococcus epidermidis phage COP-80B for preclinical evaluation of its safety and efficacy for the treatment of orthopedic-related chronic infections (Vida Štilec, COBIK)